Hi, Sparklegram. I met with my Onco and am now taking a 2-month hiatus from Anastrazole. I'm hoping the worst side effects lessen during this drug vacay! After the two months, my Onco will still recommend either staying on Arimidex or a different AI. She did mention tamoxifen also as an alternative. I generally am having a hard time accepting taking any of these anti-estrogen meds due to their many and varied side effects, and my generally not being a "pill popper" for any health issues. I guess I'll just have to suck it up and pick the one with the least side effects for the duration. Thanks.