Because of my condition, I have no menopause, and my uterus could not develop. But otherwise, I have to deal with almost any of the conditions any older woman has to deal with. Outside of the docs at the Mayo, I work with a local ob/gyn, and he is also very progressive. In addition to my estrogen I inject, he prescribed estrogen cream that I introduce into my vagina.
I discussed my situation with him, and I rather have a 0.1% risk increase for DVT, but live a normal and active life otherwise; or have a dried out vaginal mucous membrane with fissures all over it, and lots of pain and discomfort, but a tiny better chance not to get DVT.
I am amazed how little many gynecologists know about hormones and their interaction with our bodies, and how little they stayed informed about new medical knowledge.