First time user glad to know you all are there. Diagnosed with PMR November 2018 received low dose Prednisone 10 mg gradually tapered off last dose October 2020. Dr prescribed Methotrexate 10 mg November last year tolerated well but last three months developed constant tremors, and horrible taste and nausea after taking weekly dose. Lab tests well within good ranges. Fatigue is the main issue I am very fortunate to not have the long lasting pain, brain fog, depression and other associated symptoms that some of you have had. Good luck to all in the future. Michael