I was born with a certain medical condition, which causes my body to not produce any sex hormones. I am taking outside hormones for many years already (estrogen, progesterone and testosterone) , and I feel great as long as I take them. Because of a surgery, I recently had to reduce the amount of estrogen to less than a half of my normal level, and I felt pretty bad. To reduce the risk of any blood clotting and other negative side effects from estrogen, I inject it once a week. This was prescribed to me by the endocrinology department of the Mayo in Rochester. They do a quarterly test of my blood levels to make sure my hormones stay in a healthy range.
Many surgeons are very often not up on the latest knowledge concerning hormones.
I strongly recommend to work with the endocrinologists of the Mayo, because they are pretty much leading edge concerning hormones and their reaction with the body.