I had my last (the 12th) Evenity injection today. I will start on Prolia next month. Prolia is administered by injection once every six months. It is supposed to be the best thing to follow Evenity. I gather from reading on this blog that patients remain on Prolia for the rest of their lives. My doctor said that there are minimal side effects. Supposedly there may be some bone pain which I believe I experienced once years ago when I was on oral alendronate. The doctor said that if you have any bone pain it resolves or goes away after a week or so. The Evenity injections are momentarily a little painful while the medicine, which is apparently thick, is being injected. The site of the injection remains tender to the touch for a few hours but all things considered I have not felt it to be a problem and I am not a stoic person. I have had a very positive experience with Evenity. I hope it works out for you too.