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Mac question: Arikayce Inhaler Antibiotic

MAC & Bronchiectasis | Last Active: Mar 5, 2022 | Replies (73)

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@janeta

I think I understand, then, that Arikayce is a brand name of the drug Amikacin. Amakacin is given IV or injected. The inhaled Arikayce I take now is liposomal - yes, encased in a fat globule. Subjectively, I feel that the Arikayce is the most effective in bringing up - or at least just clearing - the teeny-tiny bit of sputum that I have. SO many drugs and I'm trying to learn! I think I've finally understood that there are multiple ways to treat MAC/MAI, it affects everyone differently, and that just because the Mycobacterium isn't completely gone, I can still have a somewhat fair quality of life ... that it's not a death sentence as I initially thought. THANK YOU for your comments.

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Replies to "I think I understand, then, that Arikayce is a brand name of the drug Amikacin. Amakacin..."

Actually, per my understanding, Arikayce is the brand name for ALIS (Amikacin Liposomal Inhalation Suspension). It's a more diluted better tolerated drug compared to regular Amikacin, which can also be inhaled in addition to given via IV/injection. Prior to a couple of years ago, when ALIS/Arikayce was FDA approved, the only inhalation option was regular Amikacin. Link to 2014 study on inhaled Amikacin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972984/