I did 18 months of ADT, 6x90 days shots starting In Jan 17, last shot was May 18 so by August 18 the Lupron had cleared my system. My T was 135 in October and by Feb 19 it was 482. The side affects I experienced while on Lupron, fatigue, hot flashes, genitalia shrinkage and muscle and joint stiffness began to wane three months and by six months were more or less gone.
While on Lupron I continued to exercise - biking, hiking, swimming, walks, swimming, lifting weights, skiing, basketball, yard work...I also kept an eye on my diet to keep the weight under control, checked in with my GP and Cardiologist to monitor metabolic and cardiovascular health as urologists and oncologists typically do not do that.
I chose not to take any medicine for the hot flashes, just dealt with it. Of course, I never ran the heater in my car, swam in the unheated pool, would spend time on the deck in the winter.
Thanks. This offers me encouragement that in six months things will improve for me. Ah yes, the hot flashes. Of all the side effect I deal with, that is actually one of the more manageable ones for me.