I was successfully treated for PMR with 20mg prednisone for 3 months, 15 mg for 1 month, 10 for one month; then down 1 mg per month until zero. No pain or stiffness during treatment or after. 10 weeks free from prednisone, my second Moderna vaccine caused a flare up. My doctor has started me at 15 mg prednisone, which doesn’t quite do the trick. I still have some pain in my thumbs, nearly all day. I have only been taking prednisone for 1 week at this point. My question is is it better to take less prednisone and deal with some pain, or take more and knock it out? Perhaps some of you know from experience.