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@trivia

I don't have Neuroendocrine tumors. Mine are HR + HER2-. Sorry for the confusion. My Oncologist would like to start me on Piqray because of the mutations. But there's also another drug called Afinitory for PIK3 mutation that has a domain of H1047R, which seems more successful but with more side effects. The studies have paired Piqray with Fulvestrant to cover the HR+ mutation.

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Replies to "I don't have Neuroendocrine tumors. Mine are HR + HER2-. Sorry for the confusion. My Oncologist..."

Hi @trivia,

We do have a discussion in the Breast Cancer group where others have discussed HR + HER2-. Here is the link https://connect.mayoclinic.org/discussion/her2-positive-her2-negative/
Perhaps you can find some support and additional information there.

I would like to invite @elizm @cindylb and @michmom to post with you as well.