15 TO 25 mgs prednisone is the usual starting dose for PMR, dependent upon one's weight. You have reduced too fast--and perhaps you have not taken enough to wipe up all the inflammation created by PMR. Very few get over PMR in two years. Average length is 5.9 years. Pred takes place of the cortisol produced by your adrenal glands. It sometimes takes a year for adrenals to wake up and again produce cortisol which equals 5 to 7 mgs pred. Ibuprofen is not recommended to take along with prednisone.