A rising CA 15-3 was the only indication me or my Oncologist had that something might be wrong. I felt great and all my other bloodwork was normal. But in fact, my cancer had progressed to metastatic. Without the early indicator of the CA 15 -3 we might have gone months or longer with the advancing cancer going unnoticed & untreated. I am grateful for the little bit of anxiety that resulted in an earlier diagnosis & an active treatment plan.