Anyone had nausea as a side effect of tamoxifen? What helps?

You're welcome. It's always good to ask questions. I'm sure your oncologist appreciates knowing that you want to make informed decisions.

Now, about the nausea that you experience. Does it happen before or after you take the pill at 7 or 8 am? Have you thought of slowing moving it to a different time of day?

@sparklegram and @jdriver, what time of day do you take tamoxifen? Do you find there's a better time to help manage side effects?

You're welcome. It's always good to ask questions. I'm sure your oncologist appreciates knowing that you want to make informed decisions.

Now, about the nausea that you experience. Does it happen before or after you take the pill at 7 or 8 am? Have you thought of slowing moving it to a different time of day?

@sparklegram and @jdriver, what time of day do you take tamoxifen? Do you find there's a better time to help manage side effects?

I get nauseous after i take it more so than before i take it. It’s not every day it’s more like 2-3 times a week. The other thing I didn’t tell you is I have Barrettes Esophagus and it’s pre-cancer. Last year I was very sick for about 8 months and towards the end I just about lost my voice. My Pulmonary and Oncologist thinks I may now have Esophageal cancer so I have to get tested again. So it may not be all the Tamoxifen that’s making me sick.

I recently had a lumpectomy after getting a 2nd opinion at Mayo. My former hospital did not catch it! No lymph nodes were affected and margins were considered clear however, the team suggested (as a safeguard) that I have 5 treatments of radiation followed by a low dosage of tomaxifen...5mg every other day. It seems to be a fairly new concept and wondered how others have faired with such a treatment? I guess I am apprehensive concerning the newness of this dosage and want the most successful treatment out there. Any suggestions? I also have a concern with cancer treatment affecting the thyroid meds I have taken for years. Your comments are greatly appreciated.

I recently had a lumpectomy after getting a 2nd opinion at Mayo. My former hospital did not catch it! No lymph nodes were affected and margins were considered clear however, the team suggested (as a safeguard) that I have 5 treatments of radiation followed by a low dosage of tomaxifen...5mg every other day. It seems to be a fairly new concept and wondered how others have faired with such a treatment? I guess I am apprehensive concerning the newness of this dosage and want the most successful treatment out there. Any suggestions? I also have a concern with cancer treatment affecting the thyroid meds I have taken for years. Your comments are greatly appreciated.

Welcome Creeder. I'm glad you got a second opinion at Mayo Clinic. What led you to seek a second opinion?

@mugs24cancer, researcher as early as 2018 published evidence that low-dose tamoxifen can be effective for intraepithelial neoplasia - early, non-invasive or pre-invasive cancers such as atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS), and lobular carcinoma in situ (LCIS).
- Can Low-Dose Tamoxifen Prevent Recurrences With Reduced Toxicity? https://www.cancernetwork.com/view/can-low-dose-tamoxifen-prevent-recurrences-reduced-toxicity
- 5 mg Tamoxifen as Effective as 20 mg Daily in Early Localized Breast Cancer http://www.theoncologynurse.com/breast-cancer/17686-5-mg-tamoxifen

Welcome Creeder. I'm glad you got a second opinion at Mayo Clinic. What led you to seek a second opinion?

@mugs24cancer, researcher as early as 2018 published evidence that low-dose tamoxifen can be effective for intraepithelial neoplasia - early, non-invasive or pre-invasive cancers such as atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS), and lobular carcinoma in situ (LCIS).
- Can Low-Dose Tamoxifen Prevent Recurrences With Reduced Toxicity? https://www.cancernetwork.com/view/can-low-dose-tamoxifen-prevent-recurrences-reduced-toxicity
- 5 mg Tamoxifen as Effective as 20 mg Daily in Early Localized Breast Cancer http://www.theoncologynurse.com/breast-cancer/17686-5-mg-tamoxifen

Thank you! Are there any studies that have been done as well on a lower dose of letrozole?

Oh Shirley, I'm sorry to hear that the Barrett's esophagus may have progressed to esophageal cancer. Please keep me posted as we have a group here on Connect about esophageal cancer too.

@sparklegram shared that she takes tamoxifen at night. Taking your pill later in the day may help and could be discussed with your oncologist about how best to gradually shift the time of day you take it. I know that it is advised to take it the same time of day, so you wouldn't want to make the drastic change from morning to evening in one day.