Hello, My Dr. & I are pretty certain my strong immune response caused it. Never had a problem before the fever after the 2nd Pfizer Vac. Lived with pain & stiffness for 3 months. Prednisone helping 80% at 20mg. One thing I can’t get out of my head is that my Mother developed Gullain Barre after getting a flu in 1963. Paralyzed & trached for a cpl months. May be a genetic link?

You might be interested in this discussion on the Covid 19 group - specifically the research john (@johnbishop) and I have done regarding PN and the vaccine - https://connect.mayoclinic.org/discussion/covid-vaccines-and-neuropathy/?pg=39#comment-597704
PN flares and inflammatory arthritis flares from vaccines have been reported in VAERS for over a decade, so this is not new - it's just a matter of each person figuring out if the protection is worth the discomfort.
I have reacted to both shingles and flu vaccines in the past with inflammatory flares, so was not surprised to have a similar reaction to the Pfizer vaccine. For the first time ever, my husband reacted as well. In both cases, the episodes resolved after a month or so.
Sue

I got the 1st dose of Moderna on 1/22/21 and within several days experienced severe inflammation in shoulders and hips. Diagnosis was PMR with SED rates @ 50. I fit the profile for PMR (female, late 60's, of Northern European descent), but I feel it was definitely triggered by the vaccine. Neither my Rheumatologist nor my primary physician knew whether to recommend I take the 2nd dose of Moderna, so I haven't. The catch is that I know the prednisone reduces my immunity, and I guess with only 1 part of the Moderna therapy I may have a lesser degree of immunity to the virus.
Have been taking prednisone 2x daily since then, trying to reduce it from 40 mg/day and am now at 22.5mg/day. My reactions to the prednisone seem worse than to the PMR, but my Rheumatology doctor hasn't been able to see me since I saw him in mid February. I am suffering shortness of breath, my face is very swollen, my eyes bother me, my skull feels swollen. I was reducing prednisone every 5 days, but my SED rate increased from my post original therapy of 50 to 22 with Rx, and to 41 during that period when I was reducing it. Pain was not too remarkable in the process though I could feel that shoulder pain was beginning by the time I woke up each day. Since then, on basis of SED rate, I was told to stop reducing prednisone until I could get my first follow up appointment since diagnosis. I'm uncomfortable with the prednisone and really want it reduced as quickly as possible.