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Ankylosing spondylitis: anyone else?

Spine Health | Last Active: Mar 31 1:36am | Replies (69)
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@zina

There is a blood test for AS, they test of the HLA-B27 gene. I never had any good diagnosed with regular doctors, I went to a rhumatologist and he knew right away. He says he could tell just by the way I walked. He did the blood test and I was positive for HLA- B27. I've had the pain since I was 13, now 48. I am mostly concerned with the side effect of all the drugs that are suppose to help. I don't want to trade one problem for another.

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Replies to "There is a blood test for AS, they test of the HLA-B27 gene. I never had..."
terri672 | @terri672 | Dec 22, 2020

Hi Zina... you can have the HLA-B27 gene and not have AS... "Up to 90 percent of people with the disease have the marker, which is part of a family of genes that plays a central role in the immune system. But while most people with ankylosing spondylitis have the genetic marker, only a small percentage—perhaps one to five percent—of people with the gene develop the disease, suggesting other genes and factors are involved." https://www.niams.nih.gov/newsroom/spotlight-on-research/scientists-gain-new-insights-genetic-mechanisms-ankylosing

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turdsmom3 | @turdsmom3 | May 4, 2023

HELLO, I AFTER MANY YEARS OF UNEXPLAINED ILLNESS AND PAIN WAS FINALLY TESTED FOR THIS GENE AND CAME BACK POSITIVE. IM VERY NERVOUS AND WAITING TO GET AN APPT WITH A RHUMATOLGIST. ANY SUGGESTIOS ON WHAT TO EXPECT

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