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DiscussionAnkylosing spondylitis: anyone else?
Spine Health | Last Active: Oct 21 9:35am | Replies (78)Comment receiving replies
Replies to "There is a blood test for AS, they test of the HLA-B27 gene. I never had..."
HELLO, I AFTER MANY YEARS OF UNEXPLAINED ILLNESS AND PAIN WAS FINALLY TESTED FOR THIS GENE AND CAME BACK POSITIVE. IM VERY NERVOUS AND WAITING TO GET AN APPT WITH A RHUMATOLGIST. ANY SUGGESTIOS ON WHAT TO EXPECT
Hi Zina... you can have the HLA-B27 gene and not have AS... "Up to 90 percent of people with the disease have the marker, which is part of a family of genes that plays a central role in the immune system. But while most people with ankylosing spondylitis have the genetic marker, only a small percentage—perhaps one to five percent—of people with the gene develop the disease, suggesting other genes and factors are involved." https://www.niams.nih.gov/newsroom/spotlight-on-research/scientists-gain-new-insights-genetic-mechanisms-ankylosing