I may have said this before but it continues to amaze me how differently Gastroparesis affects each of us. I am fortunate to have a more moderate case of Gastroparesis than most of you.
But I did go thru a period of time when I went back and forth between constipation and diarrhea. Yuck! The 10mg domperidone twice a day helped me with no side affects. But my doc had me taking miralax twice a day for the constipation and it was just too much and caused diarrhea. He changed it to once a day in combination with colace twice a day. Still too much.
I think you just have to figure out what’s right for you yourself. I have been taking 2 colace a day for months. I mark my calendar at bedtime each night with a check mark or an X indicating whether I did or did not have a bowel movement that day. If I don’t go for 3 straight days, I take miralax the next day. That’s what works for me.