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Event
Video Q&A about Cancer Immunotherapies Event Date: February 6, 2019 | 9:30am - 10:00am CT

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@gemma1960

When endometrial cancer metastasizes, are the mets always the same genetic makeup of the original tumor or is there a possibility of further mutations? In other words, if my original tumor has had genomic testing through an organization like Foundation One, how can I be sure that the mets that have spread to my lungs have the same abnormalities and, therefore, might benefit from an immunotherapy suggested by the genomic testing of the original tumor?

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Replies to "When endometrial cancer metastasizes, are the mets always the same genetic makeup of the original tumor..."

Hey @gemma1960, your question was sent to Dr. Gerardo Colon-Otero. Here is his response: Recent data suggest marked tumor heterogeneity in many different tumors including ovarian cancer, renal cell clear cell carcinoma and lung cancers, which makes treatment decisions based on tumor genetic analysis difficult.