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May 12, 2015 | 12:00pm - 1:00pm ET

Webinar: What Women Need to Know about Ovarian Cancer (Event)


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@lsudoublep

My mother was just diagnosed with a second recurrence, however is relatively asymptomatic (small nodule growth in mesenteric fat area)….we have been told that a hormonal therapy option might be a way to keep it stable for a bit (to delay going on chemo again)…have you used this before and if so, do you favor tamoxifen or femara?

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Replies to "My mother was just diagnosed with a second recurrence, however is relatively asymptomatic (small nodule growth..."

Your oncologist has probably pointed out that hormonal therapies as single-agents have limited activity. I typically do not use these drugs in ovarian cancer. That said, I agree with the philosophy that we should not let the treatment be worse than the disease. If there are no symptoms, there is no rush to start chemotherapy. Tamoxifen or femara treatments are generally well tolerated and if cost isn’t an issue, you might prefer this treatment over watchful-waiting.
If your mother is able to travel and is interested in a trial, we are combining letrozole (hormone blocker) with everolimus (a drug that we hope will prevent resistance to letrozole) in ovarian cancer patients who have ER-positive tumors. More information is available at
https://clinicaltrials.gov/ct2/show/study/NCT02283658