Lynch Syndrome refers to an inherited predisposition to colorectal and other cancers due to a change in one or more genes involved in DNA mismatch repair (a biologic process that helps eliminate cells with errors in their genetic code). Lynch Syndrome can be suspected based on family history, and confirmed using genetic testing. Colorectal and other cancer screening recommendations are different for Lynch Syndrome families than for the general population, so please consult a healthcare provider for a more detailed discussion if you are concerned about possible Lynch Syndrome.Paul Limburg MD