Thanks for your question, its a good one! Sometimes a treatment helps but doesn't fully treat depression. I would encourage you to talk to the doctor who prescribed the medication for you. A number of factors would go into the decision about what to do next including how long you've been on the medication, what dose you are taking, what medications you've tried in the past and which symptoms you are still having. Depending on the answers to these questions your doctor could decide to have you increase your dose, switch to a different medication, add an additional medication, consider adding psychotherapy to your treatment, or perhaps even evaluate you for some other problem (for example--if the main ongoing problem is fatigue, your doctor may want to look at the possibility of a sleep problem). So please speak up about how you are feeling so you and your doctor can discuss the right next step for you.