You have to go to a relay drug or risk vetebral fractures

@lifetimepain and @imatine. I just wanted to slide in here to add a positive post to stopping Prolia after one year and moving to the once/week dose of Alendronate. I can vouch for the fact that neither the stopping of Prolia nor the beginning of the Alendronate was accompanied by any issues. I simply waited until it was time for the next Prolia injection and substituted it with an oral pill format.

For me the Prolia side effects were exorbitant. If you recall, Prolia is administered as an every six months injection. That puts a lot of medication into your body all at once just to reach the halfway point. My body couldn't handle it. What it does handle well is a weekly pill.

Good luck with finding a positive manner by which to protect your bones.

Chris