Hi @busch and all... so odd, I read weeks ago to take Tylenol before vaccine, half hour before, another half hour after, and one at bedtime. Another bulletin said do not take Tylenol at all. So now I am wondering if it depends on the brand of the Vaccine or the patient? So confusing the information they are putting out isn't it? J.

Hi, its just that I had read not to take Tylenol before vaccine..perhaps you may wish to check into before taking? Just trying to help.
HOWEVER maybe the following does not apply for those with Neuropathy? Could someone please find out? Thanks, June

THURSDAY, Feb. 18, 2021 (HealthDay News) -- You finally managed to score an appointment to be vaccinated against the new coronavirus and you're a little nervous about side effects, so taking a painkiller right before you get your shot seems like a smart idea.
Not so fast, says the U.S. Centers for Disease Control and Prevention. Instead, the agency is telling people not to take pain medications like Motrin, Advil or Tylenol before getting their COVID-19 vaccines.
Why?
It's possible that taking a painkiller before getting a vaccine will result in a "decrease in antibody response," explained Dr. Gregory Poland, director of the Vaccine Research Group at the Mayo Clinic in Rochester, Minn.
Although the odds of a diminished immune response aren't really known, Poland said it's better to suffer the side effects than take the chance of making the vaccine less effective.

"After receiving the vaccine, if one develops symptoms that they feel they want to treat, it's fine, but ideally not before," he said. "Now, that's a recommendation by CDC, out of an abundance of caution."

There are exceptions, however: People who usually take pain relievers, such as migraine sufferers, should of course take their medication, he added. "Go ahead and take it rather than end up with a full-blown migraine and end up in the ER having to get much more intensive or expensive therapy," Poland said.