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@bustrbrwn22

Reaching out to those who use Cymbalta and Lyrica for nerve pain. What dose do you take and how long until it started working? My neuropathy is getting progressively worse and I need to try things again even if they might not have worked in the past.

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Replies to "Reaching out to those who use Cymbalta and Lyrica for nerve pain. What dose do you..."

@bustrbrwn22 Jen, You might want to try Low Dose Naltrexone. It does help some people with pain. You might also want to try an old time tricyclic anti depressant, norprimane/desipramine (They are the same.) This anti depressant is cheap and there are docs who think they work better than the newer Cymbalta or Lyrica for nerve pain. LoriRenee1

I use Cymbalta 60 mg daily and currently Lyrica 150 mg 3x daily. I will soon be increasing the Lyrica to 200 mg 3x daily.
To tell you the truth, I don't know if they help or not, and if they do, I think it's subtle. With so many variables affecting how I feel with my small fiber idiopathic PN, it's impossible to tell, unless the pain relief is fairly dramatic. I am increasing the dose of Lyrica to maximum/day to see if it makes any difference. BTW, I don't notice any side effects from the Lyrica; it doesn't even make me sleepy.
I'm sure the Cymbalta is at least helping with my mood. It's nearly impossible not to feel some depression with this disease.

@lorirenee1 mentioned low dose naltrexone. I tried that, didn't help. BTW, if you do try it, you should know it's a special order from a compounding pharmacy, which =$.