Hello @shooei, Did the GI doc say why he wanted to remove your gallbladder? I just read your original post and I think some of your symptoms could be gallbladder related. You are doing a lot of good things to keep the Bronchiectasis/MAC under control. You might try adding Mucinex along with NAC. As far as diet if you are eating animal protein you could eliminate the Famotidine and Pepsin from your regime by going with a WFPB diet (whole food plant based). Regarding the lung-gut axis question it is proven that reflux/aspiration can definitely contribute to lung problems. I don't see how lung issues could cause gut problems unless of course you are taking antibiotics for the MAC. Just my 2 cents worth. Bill