I use my vest twice a day with 3% saline nebulized. The nebulizer is attached to my Aerobika (per instructons from my pulmonologist). This is working well for me except the vest vibration can upset my stomach if done too soon after eating. Depending on my schedule, I someitmes only do the Aereobika/nebulizer combo in the evening. I don't always get mucus up during the process. Sometimes both during and after, especially if I follow up by drinking water or some other hydrating drink. No back problems for me in this process; only stomach. I have had multiple PICC line and other treatments for my pseudomonas which still show as "heavy" in the sputum culture. Doctor says it is not an active infection. He says we're keeping the pseudonomas at bay, and that seems to be the goal. I am convinced that the system I am using with the vest, nebulizer, and Aerobika is what is keeping them at bay.