My mother and aunt both had breast CA so i went through genetic testing. I have the RAD50 mutation. After discussion with breast surgeon and oncologist i changed my surgery to B mastectomy instead of lumpectomy. Apparently with the RAD50 mutation your chance of getting breast CA increases to 24%. My children and mother along with my sibling all went through the genetic testing with my Mother, daughter, both my brothers, and my niece all having the same RAD50 mutation. My daughter and niece have met with geneticists are are being set up at high risk breast clinics for screenings alternating MRIs and 3D mammography each year. They will also be screened for ovarian ca as apparently the risk for that is also slightly increased. Hope this gives you some info.