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@hopeful33250

Hello @dancingtree and welcome to Mayo Clinic Connect.

I'm glad that you posted your question about SSRI meds and bone loss. I have also taken various anti-depressants for many years but have never heard about any side effects of bone loss associated with these meds. It is important when you read an article to be sure that the source of the article (author, publisher, etc.) is reliable from a scientific/medical standpoint.

I've been told by GI doctors that meds that reduce stomach acids called PPIs (these include products like Nexium, Prilosec, etc.) which are in the class of PPI can cause bone loss over the years. Perhaps you have taken these meds as well?

As I also have bone loss and have recently started taking Actonel, I'm wondering what type of life style changes you have made in order to help reduce bone loss. I'm thinking of activities such as a diet high in calcium, also Vit D3 supplements, and weight-bearing exercises like walking.

I look forward to hearing from you again. Will you post an update?

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Replies to "Hello @dancingtree and welcome to Mayo Clinic Connect. I'm glad that you posted your question about..."

Regarding Effexor causing bone loss, the National Institute of Health stated in an article in the National Institute of Medicine that it can.

“Epidemiologic data suggest older adults receiving serotonergic antidepressants may have accelerated bone loss. We examined bone turnover marker changes and patient-level variables associated with these changes in older adults receiving protocolized antidepressant treatment.“

The same can be found in numerous other reputable articles and institutions.