I have ankylosing spondylitis. It was first suspected by my eye doctor. I had uveitis or iritis often. The iris gets inflamed and is very painful. I also had back pain so he suggested I see my doc. I had negative HLA marker so my ignorant doc said I didn't have it. After about a year I saw a rheumatologist who took x-rays and history and said yes I had it. I started taking anti-inflammatory which helped a lot. Finally had gastro bleed years later and can only take pain killers. So back gets worse with stress especially but scoliosis too. It's manageable with Ixprim for me so far.