Hello Hank and thank you for your good information as always. I would not take the 50 mg of B6 if I were you. The recommended daily requirement is only 2 mg at the most. I have been off the B6 for a week and last night had severe tetany from 11 p.m. until 11 a.m. this morning. I could find no relief. I finally went to bed at 8 this morning and slightly dozed but was fully aware that I was trying to stretch out contractions as they just would not quit. So many of these involve the big thigh muscles including inner thigh muscles (abductors) and tops of my feet and shins. I do not get them in the arches of my feet or my calves like most people do. And sometimes get them in my fingers at the same time and of course my toes. It was brutal and I have had almost no sleep. This happens far too often so it is clearly coming from another cause besides the B6 toxicity. Ugh! Onward and forward! Sunny