Hello @msskypooh and welcome to Mayo Clinic Connect. I understand you developed hives post-gallbladder surgery and are in need of relief. I am not a provider, however, I do want to ask if you have experienced difficulty breathing or a drop in blood pressure (i.e. dizziness or lightheadedness, nausea, fainting, dehydration and unusual thirst, lack of concentration, blurred vision, or cold, clammy, pale skin)? If you have any of those symptoms, I would recommend you seeking medical attention immediately for the hives.
Members like @therjes and @ken82 have been through gallbladder surgery and may have more to share from their experience.
If those more concerning symptoms above don't apply, my next question would be have you contacted your provider to make sure they know of your hives post-operation? If so, what was the recommendation?
My only symptom is the extremely itchy rash. My doctor said I was doing everything he would recommend. (Benadryl and hydrocortisone) which isn't working at all. I've gone on to use aloe sunburn lotion which seems to work better than the hydrocortisone. Some of my internet searches have found other GB patients with the same issue in the same areas. They report chronic hives that last months to years. This seems to be more than a reaction to the antiseptic they use during surgery. I'm about to put Windex on it. Ha ha