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Vaccine against MAC?

MAC & Bronchiectasis | Last Active: Dec 20, 2020 | Replies (50)

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@bolso1

Thank you for your posting @sueinmn.
It is indeed perplexing that biofilms have not received the attention that they deserve, considering that it is estimated (Lazar, V. 2011. Quorum sensing in biofilms - How to destroy the bacterial citadels or their cohesion/power? Anaerobe 17 280-285) that they are involved in around 60% of all infections and characterized by moderate intensity symptoms, chronic evolution and resistance to antibiotics.
Mainstream medicine follows mostly a brute force approach to infection management: if it's difficult then double or triple the dose and apply for longer! Fortunately, there are other approached being developed such as bacteriophages and enzymes, that could - hopefully - in the near future compliment antibiotics.

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Replies to "Thank you for your posting @sueinmn. It is indeed perplexing that biofilms have not received the..."

Most perplexing to me is that no one has engineered a replacement for the boiler/water/riser systems almost universally used in taller buildings (apartments & dorms, offices & hotels, hospitals) and ships. These have been proven wells of infection - usually listeria (Legionaires') is the first identified culprit, with MRSA and Pseudomonas aur in hospitals as well. After Covid, as places that sat vacant for a year or more come back on line, growing biofilm and bacteria in their systems, are we going to be in for a mini-epidemic of these infections?
Sue