Bolso1 and @irene5 If most of us in this group did not also suffer from bronchiectasis (most likely incurreesd by acid reflux); a mac vaccine sounds nice. But, because of the bronchiectasis, we are prone to a number of bacterial infections, not just a. mycobacterium (mac). It would have to be a wide spectrum vaccine that also covers, pseudomonas, m. fortuitum, chimaera, m. gordonae, serratia marcescens, chelonae, m. boletti, etc. See where I am going with this? A vaccine for one thing will not stop opportunistic pathogens from infecting damaged lungs.