Many thanks for your response. I'm on week 7 of Taxol and then begin the 8 weeks of AC, so it's the same treatment as yours but in reversed order. I'm 66 and do not have any BRCA genes associated with MBC. Nor do I have a family history of MBC. It came out of nowhere. My estrogen and progesterone receptors are positive, which I'm told is a good thing because after chemo I begin a 5 year prescription of hormone therapy which is designed to "starve" this particular cancer and hopefully keep it at bay. That being said I only have a 70 percent chance of surviving 5 years, so it's scary. We both have much to live for. I'm still very concerned about the long-term health risks associated with AC, so trying to learn more about it before I begin. Taxol has not been bad, so far. I learned much from a new friend, a cancer researcher in San Diego. Too much to type but if you ever want a conversation I'm open to share what I learned from him. Best of luck on your journey. I hope we are both on the right path. All the best, -Robert