@derbeltal I can hear your anxiety about all this in your writing. I don’t know if this will provide you with any sort of comfort, but changing the meds can help with ear and eye problems. And for those of us who still struggle like yourself there is always the clinical trial of Arikayce. My own life before MAC and now with MAC and medicine are very different. I think I have gone through the stages of grief ten times over! My doctor at UMASS told me there is also a new drug out there on the horizon not yet approved by the FDA for MAC. Don’t give up! @irene5