Thank you for responding with this information. The HE4 was 89 and the ROMA was 2.3. The CA 125 was 5.6 which is good. I think the issue is that many doctors do not realize how Crohn’s affects the body. From the info I have read it says that these tests are not supposed to be done for diagnostic reasons and I do not understand why the gynecologist suggested them as a first step. She did send my daughter for an ultrasound and the technician told her that she saw nothing alarming. Actually the technician seemed to know about this issue being associated with Crohn’s. I wonder if there are gynecologist that specialize in Crohn’s patients. My daughter also has PSC and takes a bunch of medicine for both diseases. That also makes me wonder if the medicines could have an effect on all this. My daughter is 45 years old and I am curious if menopause could be contributing to the Crohn’s flare as well as these other symptoms. It would be interesting to know if other people are dealing with this and have similar questions or perhaps some answers. I am wondering if I should have put this topic under ovarian cancer rather than women’s health.