starko: I spoke to my gynecology oncologist on Monday, and she pretty much confirmed what you said -- that a 4-point rise in my CA-125 results wasn't much to worry about. She said that women with ovarian/uterine cancer tend to reach different "floor" CA-125 ranges. Some women will fall within the 5-10 range as their floor; others will have a floor of 10-15, while others tend to be in the 15-20 range. My onc thinks I will fall into the latter range and that my CA-125 results will not drop any further than 15-20. She said this was fine, just so my results don't exceed 35. I will look into the HE4,S test the next time I go for chemo (Sept. 14).