stparker54:I don't think your very slight increase in CA125 should be of concern as you are still within the "normal " range, May I suggest that you ask for a HE4,S test as well. My oncologist believes this may be a better indicator of a tumor recurrence. After being free of cancer for over a year, I found my HE4,S was gradually rising, although CA125 remained normal. My oncologist put me on daily metformin and HE4,S has fallen within a normal range. I also get blood drawn for the tests every two weeks.