After two days the new prescription seems to be helping. Prescription calls for 2 pills three times a day.. but I prefer to go slowly when introducing new meds.. so I started taking 1 pill at breakfast lunch and dinner and today the same.. seems to cut down on the number of BMs and the nausea.. its only three days so will be interested in how much this prescription (Colesevelam 625) stops three years of pain and nausea..tired of having to hunt down a restroom 30 minutes after a meal when out in public.. I had just about quit being social because of it..