@tinaesims Hi Tina, I also took the big three for one year and then I think I tested positive like 6 months later also. Don't get discouraged. I just did the 7% saline solution and I swear when some bug comes back it's because I had gotten lazy with the saline. Mine has come and gone, come and gone and it all started back in 2016. It's gone again but I believe it's when I kick the saline back up to twice a day. I exercise, too, five days a week and try to eat right except for the chocolate. ( I have a terrible sweet tooth.) Nan