Thank you for your reply. Yes, I have tried tapering 1/2 mg. at a time (several times). I have spinal stenosis, and when I have a flare I can barely stand up, let alone walk. It seems like my whole body gets inflamed at once. What have you tried in addition to prednisone? Because of my stupid kidneys, I can only take Tylenol for pain (better than nothing!). Have you taken a biologic?