Hi @fde11 since I might be one of the few people here who is not sleeping at the moment I will just weigh in here on your message. From your description it does sound like you may be developing the symptoms of peripheral neuropathy in your legs. There are two tests which people who want to have a definitive diagnosis of PN can have done, a nerve conduction test or a skin punch biopsy (google can explain either of these for you) . Both can affirm or rule out sfpn. Here's a brief synopsis of sfpn: https://www.healthline.com/health/small-fiber-neuropathy . If that is what you have, then you may find it gradually getting worse over time or it might stabilize. It could even recede although that is not what happens to most of the people whose experiences I read about. My wife has it in her feet, and has bad burning, occasionally bad itching and/or pins and needles. Thankfully it has not moved up beyond her ankles yet, except once in a while. I recommend you stay in touch with ( i.e. regularly read) the Mayo Connect neuropathy discussions, and you may gain a lot of insight from people actually suffering from it, which makes a great addition to the inputs you will gain from doctors. Among the many people who I have found particularly helpful are @jimhd (who you've met) @johbishop @rwinney @artscaping @lorirenee1 (I could go on there are so many) Wish I could add more than this meagre response, but hopefully you will begin to get answers you need as you move forward speaking with these knowledgeable folks, PN is a journey and not much of a fun one I'm afraid. Best to you, Hank