Well I had 1 shot of the Lupron at Mayo MN a year and a half ago.. and the side effects are still lingering it seems.. but I need to ask them .. Thanks for your note.. to remind me it inquire... I was so glad to have the Prostate Cancer caught dead in its tracks that was my main focus at the time... a year's follow up gives me PSAs around 0.5... and that makes me feel good..