Supplements were not a treatment; L-tryptophan was the cause. It was poisoned due to a change in how the manufacturer made it. He had taken it to help with sleep. It was removed for a time by FDA from being sold but came back to shelves in another form.
He had a rash, extreme swelling of hands and lower legs (his hands looked like balloons), and unbearable pain throughout. He could barely walk. There was scleroderma, erythema multiforme 3 different times, and extreme bone loss. Essentially there was no real treatment for all the resulting consequences. He was given prednisone which caused its own serious consequences, including two surgeries. We were blessed that he survived with disability. We had been married less than five years at the time.
Needless to say, I do not trust any “food supplements” unless they are USP certified, nor most medications.