Hi Frank, My diagnosis was almost exactly the same as yours. Stage 3. Gleason 7 (4+3). PSA was 16. I had high dose Brachytherapy followed by 25 rounds of external beam therapy. I was on Lupron for 2 full years. A shot every 3 months. My last injection was January 30, 2020. I was treated at Moffitt Cancer Center in Tampa and considered a high risk patient. I had all my labs tested every 3 months. Lupron is effective but I hated the side effects. I went to the gym and / or walked as most days. Took lose dose Paxil for the hot flashes - worked well. Did crossword puzzles everyday to try to clear the mental fog. I also was given the book "Androgen Deprivation Therapy" by Richard J. Wassersug PhD which has great info. Feel free to reach out to me with any questions. Hope I can help.