Hi @trivia, @colleenyoung tagged me on your post as I also took Ibrance. Unfortunately, I’m not going to be able to offer much to the conversation as I only took five cycles before an MRI revealed extensive liver lesions, and the decision was made to move on to a chemo drug instead. It was quite a surprise as previous CT’s only showed a handful of lesions that we were following and those appeared to remain stable during the time I was on Ibrance. We had to take the approach that Ibrance was not working, but to be fair, there is no way of knowing if it did or not since we don’t know how long the degree of lesions have been there. One of the characteristics of my lobular breast cancer is that it doesn’t present itself well on imaging, and it appears in the case of my liver, we needed the detail of the MRI to see what was really going on. Best wishes to you - I hope your next scans show your lesions are decreasing in size!