@kj9 You and your sister are certainly trying to help your mom but I can see that this is a difficult situation. Do you think she might get less stressed about the appetite med over time as she did with the blood thinner? You might see if her PCP thinks that the appetite problem is associated with depression.

You don't mention your mom's age or her weight, but the low amount of calories would be a concern for any of us. You might contact her doctor's office again and see what they might suggest.

Will you keep in touch and let me know how you and your mom are doing?