@funcountess The difference between the drug store brands is that those products may have the same "active ingredients" but they don't have as much of it.
At one time I knew a young woman who worked in the spa at the Beverly Hills Hotel where they use La Prairie products that are very expensive. She gave me some very generous sized samples and people did notice a difference in my eyes without my ever saying anything! Unfortunately, the price of La Prairie is more than I care to spend. I generally use Estee Lauder but I also do use some of the drug store products like the ones by Aveeno and some others.