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HER2 positive & HER2 negative: I have both at the same time

Breast Cancer | Last Active: Jun 12, 2023 | Replies (39)
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@hopeful33250

Hello @rraw and welcome to Mayo Connect,

Is this a new diagnosis for you? Have you met with an oncologist yet to discuss your treatment options?

I would like to invite other members of the Breast Cancer discussion group to this discussion, @elizm @trixie1313 @cindylb @elsie37

Have you had surgery yet?

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Replies to "Hello @rraw and welcome to Mayo Connect, Is this a new diagnosis for you? Have you..."
rraw | @rraw | May 25, 2020

Originally diagnosed in April 2015 HR+ER+ HER2 neg. 2 surgeries/8 rounds of chemo/33 rounds of radiation and then declared NED. Started Arimidex in Jan 2016. Cancer came back in September 2019 but presented as HER2 +. I started Herceptin/Perjeta but in January 2020 we discovered more tumors and these presented as HER2 neg so we added Ibrance and faslodex. The HER2 + is responsive to treatment but the HER2 negative is progressing. Seeing local oncologist and I have been to Duke for a consultation. I am currently waiting on the results of a Foundation 1 test to determine which treatment or clinical trial might be a possible course of action. The good news is, I am experiencing no pain or obvious symptoms.

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