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Neuropathy in feet and limited toe movement?

Neuropathy | Last Active: Nov 11, 2020 | Replies (150)

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@plbelanger

Yes. I was on Gabapentin 600mg 4x daily for a few months but it didn't seem to help much. I just started Lyrica 75mg 2x daily this week but that doesn't seem to do anything either. Regarding the hammer toes, my toes aren't curled up but my big toes I can no longer move at all. When I got my nerve conduction test done at the beginning of the year I could at least sorta move one of my big toes a bit but now I can't move either. My other toes are also being increasingly difficult to move as well.

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Replies to "Yes. I was on Gabapentin 600mg 4x daily for a few months but it didn't seem..."

Same here. I was on Gabapentin 600mg 3X per day for 4 months. Never worked. Currently trying Lyrica 75mg 3X per day. That doesn't seem to help either. I do have MDS/MPN-RS-T which is an extremely rare blood overlap disease but that's an entirely different subject. I have a family history of peripheral neuropathy going back at least 5 generations. It seems to come down on the X chromosome as my mother, her mother and my great grandmother all shared the same symptoms. I was at Stony Brook Neurology (Stony Brook University Hospital) on Tuesday and saw a Neurologist who specializes in Peripheral Neuropathies. While I was there my legs started to spasm which is a good thing because the Neurologist was able to see my major "symptom." She did order several genetics tests which should happen early next week. She ordered one for CMT and HSN. Not sure what the second genetic test is but I assume its for MS and other similar disease that strip away the nerve coverings. These tests are simple swab tests much like the genetic tests people get when they do Hereditary/Ancestry testing. Apparently, genetics testing has come a long way since the earlier blood tests that were very expensive. I did have a genetics test done at the VA Hospital about three (3) years ago for CMT but the VA only looked at 24 genes. The Stony Brook Neurologist said that test was "garbage" because there are over 80 known gene mutations that cause CMT. I feel this Neurologist is determined to find out what is actually causing my neuropathy.