@hayn3705 Oh, absolutely the lack of appetite is a hallmark of taking the Big3! That is why many of us experience sometimes alarming weight loss. I had to force myself to eat for all of the 18 months I was on the meds, and for a long time thereafter.
You can find great information about living with MAC treatment here: https://www.nationaljewish.org/education/pro-ed/live-events/ntm-patient-videos
My advice - put yourself on an hourly schedule of eating a little bit of highly nutritious food. I was eating hourly - a piece of cheese, a small cup of yogurt, a few nuts, a small protein shake or bar... I especially found anything tomato-based - spaghetti, V8, etc was intolerable.
Good luck
Sue